What to pick? I'm so busy trying them all.

[poulter]

As all combos are viable, pick the skills that match your play style and give you the most enjoyment. Expect your choices to change over time as your experience with PG grows.

Some pointers:
It might be better if you pair a damage skill with a healing skill as your first set to level e.g. sword / psychology.

At /near current end-game:
My opinion based on my experience. Yours will be different. If I haven't mentioned a skill (e.g. rabbit, pig) it is because I haven't used them recently

High DPS skills: Werewolf then Fire, Priest, Archery, Hammer & Sword. Especially Fire /Priest, Hammer /Mentalism (Electricity build), Archery /Mentalism (or Druid)
High Healing: Druid, Priest, Mentalism, Psychology.
Rage Management: Ice Magic (with a healing support skill e.g Psychology or Druid). Very reliable for soloing single patrols in Gazluk Keep
'Immortal' specs: Bard with Druid or Mentalism using a Song Twist build aka 'I WIN' button build

Specialised specs: Spider /Druid (Poison build) aka DOT, DOT, DOT - I win
Pulling /'Tank': Staff /Shield, Cow with supporting heal skill, Unarmed with supporting healing skill

Feel goos specs: Animal Handling, Necromancy. Especially if you are into pet micro-management. Lots of fun to play, if you don't get frustrated from the mechanics.

My 'go to' builds: Fire /Battle Chemistry, Archery /Druid, Bard /Druid
My favourite build: Cow /Druid, Spider /Druid
Most boring build: Bard /Druid (Twist those songs and wait for the monsters to die)

Gearing and modifications:
Items are generally stat. sticks and the number of mods on your gear and which ones are critical to your survival.

Mod numbers & stacking
- The game feels to be balanced on 9 items with 3 mods each = 27 mods (applicable to the spells you use) = likely success vs. monsters at your level
A player with max crafted with augments gear can have up to 60 mods (all focussed on the spells used, often 8+ in quantity on the same spell)
e.g. the 27 mods gear equipped player dies a lot, the 60 mod player 1 or 2-shot kills the same mob most every time
Gold gear, stacking mods & augments make a huge difference to survival